biomaterials and engineering technologies

Soft (bio)materials, such as polymeric hydrogels, can be designed to recreate certain aspects of the extracellular matrix (ECM). Engineering hydrogel platforms that are mechanically and structurally dynamic allows to probe biological questions and translate our findings to medical applications.

research themes:

(i) the design of dynamic hydrogels to probe cell-ECM interactions

(ii) the development of microscale engineering tools to recreate the complexity of biological systems

Loebel, C.; Ayoub A.; Galarraga J.H.; Kossover, O.; Simaan-Yameen, H.; Seliktar, D.; Burdick, J.A. (2019) Tailoring supramolecular guest-host hydrogel viscoelasticity with covalent fibrinogen double networks . Journal of Materials Chemistry B, 7, 1753-1760

Loebel, C.*; Rodell, C.B.*; Chen, M.H.; Burdick, J.A. (2017) Shear-thinning and self-healing hydrogels as injectable therapeutics and for 3D-printing. Nature Protocols, 12(8), 1521-1541 *equal contribution

Illustration: Various hydrogels that are designed with tensile and self-healing properties (scale bars 5 mm).

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