Goal: Hydrogels as cell-adhesive sealants towards articular cartilage repair
Illustration: Applied hyaluronic acid hydrogel atop cartilage defects forms a stable sealing by interpenetrating with secreted matrix proteins (scale bars 50 µm).
Goal: Hydrogels to support orthotopic transplantation of alveolar progenitor cells
Illustration: Whole-lobe immunostain of a primary AT2 transplant recipient, showing extent of engraftment and proliferation throughout injured lobes (scale bar 1000 µm). Image modified from Weinert et. al., Nature Regenerative Medicine 2019